Researchers discovered lariocidin, a lasso peptide antibiotic that kills multidrug-resistant bacteria by binding a novel ...

The rRNA structures also provide binding sites for ribosomal proteins, which help stabilize the overall structure of the ... which catalyzes the formation of peptide bonds between amino acids during ...

The study reveals lariocidin, a potent ribosome-targeting antibiotic, with unique mechanisms that could combat drug-resistant ...

"In addition, CRISPR knockout screens showed that beyond RACK1, another ribosomal protein, RPLP2, is also important. RPLP2 is a component of an unusual extension to the ribosome called the P-stalk ...

identifying protein degradation pathways altered explicitly in disease and employing this information to develop small molecule probes with therapeutic potential, and 3) elucidating the fundamental ...

The research field of 'cellular IRESes' lay dormant for decades, as there was no uniform standard of reliable methods for the clear characterization of these starting points for the ribosome-mediated ...

Only recently has the ribosome—one of the oldest molecular machines in evolutionary terms—been recognized as an active regulator of gene expression at the level of protein biosynthesis.

Erythromycin (as base) 333mg, 500mg; del-rel tabs. Erythromycin acts by inhibition of protein synthesis by binding 50S ribosomal subunits of susceptible organisms. It does not affect nucleic acid ...