Cells activate various pathways to counter DNA replication stress. Using Replication-IDentifier (Repli-ID), the authors identified 423 genes, including LGE1 and ROX1, linking epigenetic and ...

Cancer cells display high levels of oncogene-induced replication stress (RS) and rely on DNA damage checkpoint for viability ... To identify novel small molecules that target the RS response in cancer ...

Future studies could explore ways to target and eliminate senescent cells to improve health ... This damage can lead to mutations and errors in DNA replication, thus contributing to accelerated aging ...

Breast cancers can be classified into subgroups that hint at the aggressiveness of the cancer and the likelihood that the ...

The replication crisis in psychology refers to concerns about the credibility of findings in psychological science. The term, which originated in the early 2010s, denotes that findings in ...

The UL13 protein of herpesviruses is conserved among all herpesviruses and is a serine/threonine protein kinase, which plays a vital role in escaping innate immunity and promoting viral replication.

It is an essential player in a variety of DNA replication activities, and perform major roles in the production of ... as a novel biomarker and potential therapeutic target, requires specific analysis ...

Breast cancers at all stages are defined by the structure of their genomes, researchers find. Targeting these processes early is likely to offer unexpected therapeutic avenues.

Target was one of corporate America’s most forceful supporters of diversity and inclusion initiatives and vowed to support Black Americans in the aftermath of George Floyd’s murder by police ...

Engaging in activities that support self-care may help reduce stress and anxiety. These can include getting more exercise, mindfulness practices, and eating a well-balanced diet. Minimizing the ...

Stretching, using essential oils, scanning your body for muscular tension, and foam rolling are just a few of the many ways to relieve stress — all in under 30 minutes. Stress is sneaky.