but the cell types and the signalling pathways orchestrating this bacterial regulation of intestinal homeostasis remain poorly understood. Here, we investigated the function of intestinal epithelial ...
Here we review key immune cells that maintain intestinal homeostasis and, conversely, describe how altered function and imbalances may lead to inflammatory bowel disease (IBD). We highlight the latest ...
Background and aims: Patients with Crohn’s disease (CD) exhibit excessive apoptosis of intestinal epithelial cells (IECs), which contributes to damage to the intestinal barrier structure and function, ...
Intestinal probiotics are a type of active microorganisms beneficial to the health of the host and an essential element of human health. Reportedly, intestinal probiotics can affect the renewal of ...
Intestinal stem cells are multipotent adult stem cells, which in mammals reside in the base of the crypts of the adult intestine. Intestinal stem cells continuously self-renew by dividing and ...
Revised: This Reviewed Preprint has been revised by the authors in response to the previous round of peer review; the eLife assessment and the public reviews have been updated where necessary by the ...
Supplementary Figure 4. Glial ablation induces colonic expression of Lyz1 at the transcript, but not protein, level. A) Violin plots of Lyz1 expression in small intestine epithelial cells show ...
We demonstrated that NMNs exhibit robust superoxide dismutase (SOD)-mimicking and radical scavenging activities and that dietary NMNs improve cognition and memory functions, inhibit related ...
PROX1+ cells in intestinal adenomas of ApcMin/+ mice expressed intestinal epithelial and CRC stem cell markers, and cells with high PROX1 expression could both self-renew tumor stem/progenitor cells ...
Rich in protein and low in calories, soy milk benefits may include aiding in the reduction of high blood pressure, lowering cholesterol, combating inflammation, preventing hormone-related cancers, and ...