Intracellular kinases play a ubiquitous role in signaling pathways within cells. Receptor tyrosine kinases function at the beginning of a number of signal transduction cascades, whereas ...

The molecular basis of phospho-tyrosyl-regulation of Src-family and Syk-family protein tyrosine kinases in signaling pathways is a current focus of ... We are also actively investigating the ...

Transmembrane signaling systems include membrane ... The discovery of receptor tyrosine kinases: Targets for cancer therapy. Nature Reviews Cancer 4, 361–370 (2004) doi:10.1038/nrc1360.

“Signaling by Receptor Tyrosine Kinases” edited by Joseph Schlessinger and Mark A. Lemmon, Cold Spring Harbor Laboratory Press, ISBN978-1-936113-33-0, pages 287-303, (2014). Xu K, Tzvetkova-Robev D, ...

Pharmaceutical ads are difficult to avoid in American television programming and a growing number of them promote a class of ...

Sorafenib is an oral multikinase inhibitor that inhibits tumor growth and proliferation by interfering with several receptor tyrosine kinases involved in the pathogenesis and perpetuation of ...

Dr. Weickert will present Pacylex at the OBIO® Investment Summit and Early Technology Showcase February 5-7, 2025, at the Arcadian Court & Loft, Toronto Mr. Kamdar will present Pacylex at the PWMC ...