ABSTRAC: Fibroblasts from the original sialuria patientare shown to contain high levels of free sialic acid, i.e., anaverage of 87 versus a normal average of 2 nmol/mg ofprotein. Gas liquid ...

In early December 2024, a group of researchers published an article in the journal Science, entitled “A single mutation in ...

Sialic acids are a family of alpha-keto acid sugars with a nine-carbon backbone, functioning as terminal sugars on cell surface glycoproteins and glycan receptors for cellular recognition.

The research confirms that H5N1 hemagglutinin exhibits a strong binding affinity for sialic acid receptors present in cattle, indicating a significant risk for cross-species transmission. While the ...

Here, we utilize lectin blots to show that sialic acid residues, which are the terminal caps of glycosylation chains, are increased on neutrophil membrane proteins from an amyloidosis Alzheimer’s ...

stability and receptor binding (Varki et al., 2017). However, plants are unable to perform β1,4-galactosylation, which in mammals serves as acceptor substrate for terminal N-glycan sialylation.