Anillin (ANLN), a mitotic protein that regulates contractile ring assembly, has been reported as an oncoprotein. However, the function of ANLN in cancer cells, especially in the nucleus, has not been ...

The process of transcription elongation by RNA polymerase II (Pol II), in which Pol II travels along DNA and synthesizes RNA from DNA, is essential for proper gene expression in all eukaryotic cells.

在这里，作者报道了核ANLN通过与RNA Pol II相互作用并促进其聚类和相分离在基因转录 ... 的研究人员在Nature Communications期刊上发表了题为 “Nuclear ANLN regulates transcription initiation related Pol II clustering and target gene expression” ...

In eukaryotic cells, RNA polymerase II synthesizes mRNA in three stages ... Here, we present a quantitative analysis method to extract kinetic rates of transcription from time-lapse imaging data of ...

Lysakovskaia等人使用多组学方法研究了RNA聚合酶II的启动子-近端终止，并表明这是一个受调控的过程，可以在人类细胞类型转换事件中促进基因的上调和下调。 想象一下，细胞就像一个充满活力的小宇宙，而基因表达就是这个宇宙的引擎。Pol II就是这个引擎的 ...

After hours: February 14 at 6:27:18 PM EST Loading Chart for RNA ...

HBx binds the promoter region of the DLEU2 lncRNA, enhances DLEU2 transcription and induces the accumulation of DLEU2 RNA. HBx directly binds DLEU2 and functionally competes with EZH2 for partially ...