还有一类癌症,它们本身携带野生型的RB1基因,但在表型上类似于RB1缺陷型的癌症。英国癌症研究所的研究人员将这类癌症称为“RBness”,并利用蛋白质基因组学方法总结出它们的特征。 RB1(视网膜母细胞瘤基因1)是第一个被克隆的抑癌基因。在许多癌症类型 ...
Protein phosphorylation is a covalent post-translational modification event that is essential for regulation and maintenance of most biological processes in eukaryotes 1. Conventionally ...