The Shu complex binds to replication origins, where it interacts with the MCM and ORC complexes. The Shu complex subunit Psy3, a Rad51 paralog, mediates interaction with MCM or ORC complex. This ...

The Shu complex binds to replication origins, where it interacts with the MCM and ORC complexes. The Shu complex subunit Psy3, a Rad51 paralog, mediates interaction with MCM or ORC complex. This ...

MFI of yH2AX is an appropriate measurement for replication stress, it's just not appropriate to equate MFI to foci. We apologize for this labeling error, which has now been corrected. (5) For the ...

[Editors' note: this paper was reviewed by Review Commons.] Cancer cells display high levels of oncogene-induced replication stress (RS) and rely on DNA damage checkpoint for viability. This feature ...

Engaging in activities that support self-care may help reduce stress and anxiety. These can include getting more exercise, mindfulness practices, and eating a well-balanced diet. Minimizing the ...

Your emotions can indicate when you’re under too much stress. For example, feeling irritable or overwhelmingly fearful can be signs of stress. Stress, defined as emotional tension or mental ...

A stress fracture is generally the result of overuse or repeated trauma to a bone. Also known as "fatigue fractures," stress fractures may occur when muscles become fatigued or overloaded and transfer ...

We all know stress messes with our heads, but did you know it can also wreak havoc on our bodies? Say hello to cortisol, the hormone released when stress hits, triggering that familiar “fight ...

The replication crisis in psychology refers to concerns about the credibility of findings in psychological science. The term, which originated in the early 2010s, denotes that findings in ...

As a result, says Aditi Nerurkar, a lecturer at Harvard University and author of The 5 Resets: Rewire Your Brain and Body for Less Stress and More Resilience, around 96 percent of us are facing at ...