by activating pyruvate dehydrogenase kinase 1 (PDK1), thereby blocking pyruvate dehydrogenase (PDH) activity and limiting tricarboxylic acid (TCA) cycle flux. Reactive oxygen species (ROS) produced by ...

Such an interaction would suggest that these glycolysis/tricarboxylic acid cycle (TCA) metabolites are relevant primarily in the setting of high PRS, establishing them as resilience factors against ...

Overexpression a gene encoding the NAD+-dependent GAPDH together with three other genes (encoding malate dehydrogenase, pyruvate-formate lyase, and formate dehydrogenase ... in the MA-GAPDH1 and ...

Demographic and clinical characteristics in 2006-2010 of participants among the bottom 50% of glaucoma polygenic risk score (PRS). Interaction of three putative resilient metabolites (lactate, ...

The cycle of abuse includes four stages—tension building, abuse, reconciliation, and calm—that allow abusers to control their victims through fear and manipulation. This pattern can trap victims and ...

School of Biological Sciences and Biotechnology, Graduate School, Chonnam National University, Gwangju 61186, Republic of Korea Institute of Synthetic Biology for Carbon Neutralization, Chonnam ...

The Truckload Carriers Association (TCA) recognized 48 North American truckload carriers — including nine from Canada — as the 2025 Elite Fleets. Developed in partnership with the University of Denver ...

在人体万亿个细胞的深处，隐藏着直径仅万分之一毫米的"能量之门"——线粒体丙酮酸载体（Mitochondrial Pyruvate Carrier, MPC）。这个由两个亚基构成的 ...

There will be no TCA press tours in 2025 as Hollywood looks for ways to cut costs. By Tony Maglio The latest example of cost-cutting and consolidation in Hollywood? The canceled Television Critics ...