Etiology: The cause of granuloma annulare is unknown. Granuloma annulare can occur at any age, but is seen predominantly in children and young adults. It occurs more frequently in females than males.

[89] A 64-year-old female with granuloma faciale was successfully treated with 0.1% topical tacrolimus ointment applied twice daily; there was almost complete resolution after 2 months, and the ...