Figure 1: Plots of isotropic B factors calculated for protein structures solved in both the native and methylated states. We showed in this large-scale study that reductive methylation of proteins ...

The protein is the MCJ (Methylation-controlled J) protein, and it was highlighted by a team led by researchers from the ...

A urinary DNA methylation test demonstrated a high sensitivity for detecting high-grade or invasive bladder cancer, ...

It has already been demonstrated that the mRNA that provides the instructions for the synthesis of this protein can undergo methylation. In body cells, mRNA carries the genetic information and ...

Metabolism can change when an acetyl group attaches to lysine in a mitochondrial protein (acetylation). The addition of a methyl group to histone peptides (methylation) regulates gene expression. And ...

View Full Profile. Learn about our Editorial Policies. “This study really provides the first look at how methylation and epigenetic modification of the DNA eventually have an impact on the protein ...

Yoshiki Ochiai, the paper's first author and Ph.D. student in the Protein Engineering and Evolution Unit, tried to improve RNA methylation activity of a bacterial non-site-specific DNA ...

at CNIO and the National Centre for Cardiovascular Research (CNIC), found that the mechanism is controlled by a mitochondrial protein, methylation-controlled J protein (MCJ). Their experiments ...

Predictive methylation signature for gemcitabine sensitivity in pancreatic ductal adenocarcinoma: A pathway to personalized treatment. This is an ASCO Meeting Abstract from the 2025 ASCO ...