Figure 1: Plots of isotropic B factors calculated for protein structures solved in both the native and methylated states. We showed in this large-scale study that reductive methylation of proteins ...

Lysine methylation is a significant posttranslational modification that plays a crucial role in regulating various cellular processes, including gene expression, protein stability, and cellular ...

Scientists are tackling society's growing obesity problem from all kinds of angles – and new research picks out a particular ...

It has already been demonstrated that the mRNA that provides the instructions for the synthesis of this protein can undergo methylation. In body cells, mRNA carries the genetic information and ...

Metabolism can change when an acetyl group attaches to lysine in a mitochondrial protein (acetylation). The addition of a methyl group to histone peptides (methylation) regulates gene expression. And ...

Yoshiki Ochiai, the paper's first author and Ph.D. student in the Protein Engineering and Evolution Unit, tried to improve RNA methylation activity of a bacterial non-site-specific DNA ...

at CNIO and the National Centre for Cardiovascular Research (CNIC), found that the mechanism is controlled by a mitochondrial protein, methylation-controlled J protein (MCJ). Their experiments ...

Comparisons with DNA methylation-based predictors indicated ... genes such as Homeobox D8 (HOXD8), Thioredoxin Interacting Protein (TXNIP), and Period Circadian Regulator 1 (PER1) were strongly ...