Our guts are home to trillions of bacteria, and research over the last few decades has established how essential they are to our physiology – in health and disease.

Decades of research have disclosed a plethora of alterations in protein glycosylation that decisively impact in all stages of disease and ultimately contribute to more aggressive cell phenotypes. The ...

By employing a novel technique to examine how carbohydrates modify proteins, scientists have found that gut bacteria can ...

Following glycosylation in the ER, the protein is then transported through the Golgi apparatus, in which other glycosyltransferases and glycosidases can add, remove or modify the basal glycosylation ...

Analytical Research Center for Organic and Biological Molecules, State Key Laboratory of Drug Research, Carbohydrate-Based Drug Research Center, Shanghai Institute of Materia Medica, Chinese Academy ...

These glycans protect gut epithelial cells from chemical, biological and physical insults and are continuously renewed. Pathogens colonise and invade the host epithelial cells using protein–protein ...

As a functional assay the authors focus on viral infection starting from the assumption that a physical boundary modulated by overexpressing a protein-of-interest could prevent viral entry and ...