The primitive streak—a structure that emerges in mammalian and avian embryos to help assign spatial information to cells during early development—has long been regarded as essential for the genesis of ...

One of the earliest signs of gastrulation in reptiles, birds and mammals (amniotes) is the appearance of a thickening at the midline of the developing embryo, the primitive streak. Here ...

The little clump of cells looked almost like a human embryo ... The primitive streak—a developmental precursor of the ...

Statins inhibit the induction of primitive streak genes by suppressing protein farnesylation. Consistent with our observations, Hmgcr KO mice and FTase KO mice are embryonic lethal at E8.5 and E7 ...

As division continues, some cells divide into the growing mass, distinguishing cells that form the embryo (epiblast) from those that form the placenta (trophectoderm). Further cell divisions lead to ...