A stash of neurotransmitter-packed vesicles hunkers close to the presynaptic membrane so the vesicles can fuse with the membrane and release their cargo as soon as an electrical impulse pulls the ...

like vesicles at bona fide synaptic terminals. One reason for skepticism in evaluating factors that induce presynaptic differentiation in vitro is the evidence that non-specific factors ...

To do this, the synaptic vesicle must dock at the membrane of the presynaptic neuron and dump its content into the synapse, where it moves to particular receptors on the postsynaptic neuron.

At excitatory synapses in the cerebral cortex, the most numerous synapses in our brain, the presynaptic nerve ending contains several tens to a few hundreds of synaptic vesicles filled with the ...

There are two types of removal: Re-uptake – the neurotransmitter is reabsorbed back into the presynaptic neuron and restored inside a vesicle ready to be used again. For example, noradrenaline.