[59] Larger trials are necessary to confirm the existence of platelet resistance to prasugrel and to describe the possible underlining mechanisms. Elinogrel (PRT060128 or PRT128) (Figure 3 ...

The acquisition of resistance to anoikis, the cell death induced by loss of adhesion to the extracellular matrix, is an absolute requirement for the survival of disseminating and circulating tumour ...

Until recently, research has focused on uncovering individual pathways to target. As more of the pathophysiology of sepsis has become understood and more biomarkers uncovered, the interplay between ...