many mutations in rod photoreceptor-specific genes cause degeneration of other neuronal types. Identifying mechanisms of cell–cell interactions initiated by rod-specific mutations and affecting ...

Calcium sensor proteins play a crucial role in the functioning of photoreceptor cells, which are essential for vision. These proteins, particularly the guanylate cyclase-activating proteins (GCAPs ...

A type of pineal photoreceptor cell that contains a protein called parapinopsin 1 (PP1) detects color. These PP1 cells become active and inactive in proportion to the difference in wavelength of ...

We see color because photoreceptor cones in our eyes detect light waves corresponding to red, green, and blue, while dimness or brightness is detected by photoreceptor rods. Many non-mammalian ...

Inherited retinal diseases (IRDs) are a group of monogenic disorders caused by mutations in more than 280 genes, and are characterized by progressive degeneration of photoreceptor cells in the retina.

A type of pineal photoreceptor cell that contains a protein called parapinopsin 1 (PP1) detects color. These PP1 cells become active and inactive in proportion to the difference in wavelength of ...

Lineage Cell Therapeutics, Inc. (NYSE American and TASE: LCTX), a clinical-stage biotechnology company developing allogeneic ...

In view of the fact that RPE cell dysfunction/loss is believed to precede photoreceptor cell dysfunction/loss in STGD1 and that RPE cells can be generated in the laboratory relatively easily, a Phase ...

The companies will work together by using the codon-optimized BBS1 AAV9 vector to minimize the vision loss caused by the genetic defects in the BBS1 gene.