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Limestone Street, Rm 430, Lexington, KY 40536, USA; gregorybix{at}uky.edu Background Nitroglycerin (also known as glyceryl trinitrate (GTN)), a vasodilator best known for treatment of ischemic heart ...

The introduction of inhibitors of the cyclic GMP phosphodiesterase (PDE) 5 into clinical urology is mainly the result of the characterization of the physiology of nonvascular and vascular penile ...

You get the Puma Fast-RB (‘rule breaking’) Nitro Elite – an unashamed, attention-grabbing shoe designed specifically for those who want to run rapidly and rebelliously. First launched in ...

Aromatase is an enzyme that converts testosterone to estradiol, a type of estrogen. One study found that taking an estrogen blocker called an aromatase inhibitor while on testosterone therapy reduced ...

State Key Laboratory of Natural Medicines and Jiangsu Key Laboratory of Drug Design and Optimization, China Pharmaceutical University, Nanjing 210009, China Department of Medicinal Chemistry, School ...

However, the conserved minor venom components, such as snake venom phosphodiesterase (svPDE), remain largely unexplored ... 2020) could also function via the inhibition of svPDE by chelating zinc ions ...

Pan-caspase inhibitor, a Phosphodiesterase inhibitor, and TGF-β signaling inhibitors. FIGURE 3. Potential candidates for hepatic fibrosis and their mechanisms of action. Inhibiting the activation and ...