Get Instant Summarized Text (Gist) Pancreatic cells can retain epigenetic marks linked to cancer without genetic mutations. These marks, observed in a transition state between normal and cancerous ...

Pancreatic cells 'remember' epigenetic precancerous marks without genetic sequence mutations Date: April 4, 2025 Source: Johns Hopkins Medicine Summary: Scientists say they have found a pattern of ...

Upon exposure to a vaccine or pathogen, B cells scramble to refine their defenses, rapidly mutating in hopes of generating the most effective antibodies. But each round of this process is a roll ...

When the transitioning cells returned to their original identity as acinar cells, the scientists found that some of the epigenetic marks on pancreatic cancer-linked genes remained for at least ...

City of Hope researchers demonstrate proof of concept for a novel targeted therapy for pancreatic cancer, exploiting transcription-replication conflicts to combat treatment resistance.

Scientists have developed a new method for identifying and classifying pancreatic cancer cell subtypes based on sugars found on the outside of cancer cells. These sugars, called glycans, help cells ...

This important study shows that nutrient stress emanating from the microenvironment induces metabolic vulnerabilities in pancreatic ductal adenocarcinoma (PDAC). Using a combination of cell-based and ...

Metabolic and immune functions of GOT2 in pancreatic cancer cells. First, GOT2 catalyzes transamination reaction in ...

The cancer-fighting device safely triggers "potent" immune responses against hard-to-treat cancers, including metastatic ...

Using a pancreatic islet transplantation model ... and explore the interactions of these synthetic T cells with other antibodies and B cells. The researchers believe these engineered cells could ...