Targeting mitochondrial retrograde signaling may therefore be promising in the treatment or prevention of metabolic disorders ...

List of Confirmed and Putative Signal Transducer and Activator of Transcription (STAT)5-Target Genes in β-cells or Pancreatic Islets (Activated or Repressed Genes) Target genes of prolactin or ...

Researchers at the University of Michigan used mice to show that dysfunctional mitochondria trigger a response that affects ...

Pancreatic cancer patients may benefit from future precision treatments as a new study shows how some tumors may potentially ...

Signal transducer and activator of transcription (STAT)5A and -5B are latent transcription factors expressed in pancreatic β-cells and other tissues. Prolactin and growth hormone binding to their ...

Conceptual diagram summarizing the central experiment comparing cell death in amyloid-β treated neuronal cells with and without pancreatic β cell culture supernatant. Pancreas cells may produce ...

The distinct population of endothelial cells that line blood vessels in the insulin-producing "islets" of the human pancreas have been notoriously difficult to study, but Weill Cornell Medicine ...

The researchers were able to recreate a complete structure that includes the three key cell types in the pancreas, which previous organoids couldn't fully mimic. Notably, the team identified a new ...

Mitochondria are essential for generating energy that fuels cells and helps them function. Mitochondria are essential for generating energy that fuels cells and helps them function.