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在微观的细胞宇宙中，一个名为PTEN（Phosphatase and tensin homolog）的蛋白质如同精密的分子刹车，时刻调控着细胞增殖与存亡。这个仅有403个氨基酸的"生命守护者"，通过拮抗PI3K/AKT/mTOR信号通路，在胚胎发育、突触可塑性乃至肿瘤抑制中扮演关键角色。然而令人惊讶的是，尽管30%的癌症和多种神经发育疾病（如自闭症、癫痫）与PTEN功能异常密切相关，研究人员却长期 ...

研究人员将目光聚焦于膀胱癌中常见的 p53 突变。在膀胱癌里，超过60%的 p53 突变属于错义突变，然而此前多数小鼠模型是 p53 基因敲除模型，针对 p53 ...

为明确 PTEN 错构瘤肿瘤综合征（PHTS）中非成分癌症（NCC）情况，研究人员开展相关研究，发现其 NCC 谱，具重要意义。 PTEN 错构瘤肿瘤综合征（PTEN hamartoma tumor syndrome，PHTS）听起来或许有些陌生，但它却与多种癌症的发生息息相关。PHTS 是一类由致病的种系 PTEN ...

In a report released on March 10, Saurabh Pant from Bank of America Securities maintained a Buy rating on Patterson-UTI (PTEN – Research ...

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A novel scientific method developed at Tel Aviv University promises to accelerate our understanding of the gene PTEN, a key player in cellular growth. This breakthrough will help scientists better ...

A new study reveals that men are over twice as likely to develop Parkinson's disease compared to women, due to aggressive T ...

Patterson-UTI (PTEN) reported that for the month of February 2025, the company had an average of 107 drilling rigs operating in the United ...

The researchers predicted that the new tool will enable the development of personalized therapeutics by monitoring PTEN ...