the authors used a combination of in vivo and ex vivo experiments in mice to demonstrate ligand-independent activation of Notch1 by circulation induced-mechanical stress and provide evidence for ...

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Understanding the molecular mechanisms of insulin resistance remains a major medical challenge of the twenty-first century. Over the last half-century, many hypotheses have been proposed to ...

It was observed that Yoda1 could promote the proliferation and partial EMT of hepatocytes through the EGFR signaling pathway. Further investigation revealed that AREG and EREG enhanced the ...

Researchers have found in a recent study that intermittent fasting (IF) diminishes platelet activation and the risk of ...

4) Some subunit of the mARS complex such as AIMp1, LySRS and LeuRS are secreted, performing their regulatory roles in a paracrine fashion. What is the secretory pathway(s) through which these subunits ...