多支聚酰胺（H-PAMAM）是一种具有树枝状、高分支结构和多个活性末端基团的超支化聚合物，具有良好的生物相容性和高药物负载能力，广泛应用于药物递送和基因治疗领域。负载多柔比星（DOX）的多支聚酰胺（H-PAMAM）**是一种基于树枝状高分子材料设计的高效 ...

In the following manuscript, Zahr and Li et al. develop polycation-based polyamidoamine (PAMAM) dendrimers conjugated with an atherosclerotic plaque-homing peptide Lyp1 for the treatment of ...

SP94-PEG-DSPE是由SP94肽、聚乙二醇（PEG）和二十二碳烯基磷脂酰乙醇胺（DSPE）组成的复合物。SP94是一种具有靶向性的肽，通常用于与某些细胞表面特定受体结合，促进药物的靶向递送。通过将SP94与PEG和DSPE结合，能够制作出一种既能靶向特定受体，又具备良好生物 ...

Suzhou First People’s Hospital, School of Medicine, Anhui University of Science and Technology, 168 Taifeng Street, Shannan New District, Huainan, Anhui 232000, P. R. China Suzhou First People’s ...

双模态探针的构建与表征：研究人员以 PAMAM G2-NH?树枝状聚合物为基础，经过一系列修饰，成功构建了双模态探针 ICG-Gd-Den@DC-G16-11。扫描透射电子显微镜（STEM）等技术显示，该探针形态均匀，粒径约为 19.45±7.76nm，表面带正电荷，为 26.04±3.36mV ，在模拟生理条件下 ...

Prof. John A. Katzenellenbogen’s career has spanned over 55 years and his work has led to 576 publications and 71 reviews and book chapters. His contributions to medicinal chemistry and bioorganic ...