很多人知道高血压患者需要服用降压药来控制血压，但你有没有想过，降压药和某些食物，尤其是柚子，之间会有什么样的“化学反应”呢？ 这个问题听起来可能有点吓人，但实际上，吃柚子真的会影响降压药的效果吗？

The FDA has approved Journavx 50 mg oral tablets for the treatment of moderate to severe acute pain in adults, according to a ...

他汀类药物多需要通过肝脏进行分解代谢，代谢过程需要细胞色素P4503A4参与。柚子内的呋喃香豆素成分会抑制细胞色素P450 3A4酶的活性，从而会影响他汀的正常代谢，会增加多种副作用的发生风险。

St. John’s wort induces (increases the activity of) an enzyme called cytochrome P450 3A4. This enzyme metabolizes (breaks down) lots of medicines in the body. If these medicines are taken with St.

5-hydroxyomeprazole is then transformed into 5-hydroxyomeprazole sulfone by CYP3A4. Omeprazole is metabolized directly in part by CYP3A4 to omeprazole sulfone, then transformed into 5 ...

了解服药期间避免食用柚子的重要性，柚子中的成分会抑制CYP3A4酶活性，导致药物蓄积和副作用增加，特别是他汀类降脂药和降压药。确保用药安全，选择苹果、香蕉等替代水果。