To investigate these surprising findings in more detail, we established a murine model based on tumor organoids that resembles the clinical setting. In this murine orthotopic transplantation model for ...

Two fundamentally different surgical approaches to liver transplantation exist: (1) orthotopic (OLT), and (2) heterotopic (HLT). In OLT, the patient's diseased liver is completely removed and ...

Sorted metaplastic cells grew poorly with no progression to dysplasia, while mutant progenitors gave rise to dysplasia in orthotopic transplantation. Computational analyses indicated that p53 mutation ...

Current research on neutrophils primarily utilizes murine orthotopic transplant tumor models, but future studies should extend to human gliomas. The types of immune cell infiltrates vary across ...

Meet the transplant team: surgeons, physicians, nurses, administrators and staff. Every 10 minutes, another name is added to the national organ transplant waiting list. Each day, 21 people die from ...

The two other patients who have received pig kidneys ‒ one at NYU Langone and one at Massachusetts General Hospital ‒ died or had their transplant removed within eight weeks, as did two men ...

Hereditary hemochromatosis is an inherited iron overload disorder caused by inappropriately low hepcidin secretion leading to increased duodenal absorption of dietary iron, most commonly in C282Y ...

Age, sex and race also impact clinical outcomes, and patient morbidity and mortality are reflected by high need for gastroenterology, hepatology and organ transplant services. Epidemiology studies ...

Patients with advanced heart failure have a dismal prognosis and poor quality of life. Heart transplantation provides an effective treatment for a subset of these patients. This article provides ...

This is in contrast to the strain variation seen for the transplantation of rat kidneys and hearts and indicates that rejection of xenograft skin involves a different or an additional immune ...