KOLOA, Hawaii — In this Healio Video Perspective from Retina 2025, Roger A. Goldberg, MD, MBA, discusses the role of multimodal imaging in geographic atrophy in the era of complement inhibitors.

The continued evolution of treatment protocols and imaging modalities for the management of retinal diseases offer ... for the management of geographic atrophy secondary to age-related macular ...

In the 5 patients with bilateral geographic atrophy (GA) who received a K8 implant in 1 eye, there was a mean reduction in GA lesion growth of 66% at 3 months.

Positive efficacy and safety data were observed at 3 months after a single injection of K8 in this study conducted at the University of Kentucky.

The financing will go toward its ongoing phase 2b/3 and planned pivotal phase 3 clinical trial for AVD-104.

Conclusions SD-OCT ... imaging, remain unclear. Therapeutic intervention in order to modify the retinal lesions detected with high-resolution imaging may only be justified if these abnormalities ...

It advances to geographic atrophy (GA) in some cases. Both conditions damage the macula, the area of the retina responsible for sharp central vision. However, GA involves more significant and ...

Methods Thirty eyes (21 patients) with a diagnosis of geographic atrophy (GA ... further confirmed by spectral-domain optical coherence tomography (SD-OCT) examination, which revealed the concomitant ...

in eyes with geographic atrophy (GA) found that GA can cause a loss of 2 to 3 lines of visual acuity (VA) within 36 months of follow-up, according to first author Aumer Shughoury, MD, from Indiana ...

Imaging features associated with progression to geographic atrophy in ... Reliability of retinal layer annotation with a novel, high-resolution optical coherence tomography device: a comparative ...