Drawing from epidemiological evidence indicating that the majority of individuals with latent TB infection do not progress to active TB but remain at risk, our discussion framework centers on the host ...
Although DC-SIGN plays important roles in Mycobacterium tuberculosis (Mtb) interactions with dendritic cells, its contribution to the Mtb–macrophage interaction remains poorly understood. Since high ...
The management of Leishmania donova ni (LD), responsible for fatal visceral leishmaniasis (VL), faces increasing challenges due to rising drug-unresponsiveness, leading to increasing treatment ...
Several therapeutic advances have been achieved over the past two decades for inflammatory bowel disease (IBD). The expanding ...
Table 1. Tumor necrosis factor antagonists. Data from [201].
Therapy of tuberculosis is challenging, mainly due to complex structures of necrotic granulomas that often impair drug delivery. In this work, the authors show that the drug BTZ-043 fully ...
Drug therapy (or pharmacotherapy) involves the administration of drugs to treat or prevent disease. In some cases – often in the treatment of disease such as cancer, HIV infection and diabetes ...