The mouse model closely mimics the specific dysferlin mutation and resulting disease, and enabled the researchers to evaluate how the complete therapy works—taking muscle stem cells, correcting ...

Figure 2: Genetic map of 5p15.1 and genomic organization of ANKH. Figure 3: Cosegregation of ANKH mutations with the CMD phenotype. All eight families with mutations in ANKH are shown. We ...

Silexion Therapeutics Corp. (NASDAQ:SLXN) released new preclinical data for SIL-204, its next-generation siRNA therapeutic ...

The only natural host of the hepatitis C virus (HCV) is humans. Model organisms for laboratory studies, especially mice, ...

This fundamental work presents two clinically relevant BMP4 mutations that contribute to vertebrate development. The convincing evidence supports that the site-specific cleavage at the BMP4 pro-domain ...

A team of stem cell scientists have successfully used embryonic stem cell engineering to create a bi-paternal mouse—a mouse ...

In two new papers, researchers from The Jackson Laboratory (JAX) report the successful use of two approaches -- gene therapy ...

Scientists say identification of two epigenetically different states in mouse model opens door to "entirely new world of ...