Mitochondrial stress disrupts insulin production in diabetes, but reversing the damage may restore β-cell function.

The team demonstrated this both in mouse liver cancer cells and in several human cancer cell lines. The findings are published in the journal Nature Metabolism. However, when the researchers ...

Xinning Zhang and Ashley Maloney discovered that a geology technique shows promise in detecting cancer-like cells. If their ...

The team repeated their mouse experiments in liver cells and fat-storing cells and saw that the same stress response was ...

Gene editing is already being used to treat a handful of rare genetic diseases; however, most therapies involve breaking or ...

Scientists at EMBL and DKFZ have discovered how cells in the liver maintain their identity and avoid becoming tumour cells ...

Liver issues, including a buildup of fat in the liver, occur before the onset of neuromuscular disease, per a study in a ...

Researchers developed a new gene-editing strategy that dramatically boosts the effectiveness of gene therapies in the liver, a breakthrough that could lead to new treatments for about 700 genetic ...

A new drug delivery system shows promise for treating a rare, aggressive form of cancer affecting pregnant women and new ...

Targeting mitochondrial retrograde signaling may therefore be promising in the treatment or prevention of metabolic disorders.