Innate sensing of HIV-1 triggers an inflammatory cascade involving macrophages, monocytes, and dendritic cells that activate T cells and other innate effectors, such as NK cells (9). The importance of ...

Introduction: Dendritic cells (DCs) play a crucial role in orchestrating immune responses by bridging ... Results: Adherent chicken PBMCs were cultured with recombinant chicken granulocyte-macrophage ...

dendritic cells, eosinophils, Langerhans cells, mast cells, monocytes and macrophages, neutrophils and NK cells. Monocyte-derived alveolar macrophages (Mo-AMs) are involved in lung injury and ...

Moreover, the synovitis and macrophage accumulation were observed in the joints of 9-month-old R3cKO mice when the articular cartilage was not grossly destructed. FGFR3 deficiency in myeloid cells ...

Results Ageing causes a shift in macrophage polarisation from anti-inflammatory ‘M2’ to proinflammatory ‘M1’ that is associated with a rise in cytokines and immune cells in the ENS. This phenotypic ...

in macrophage and dendritic cell subsets. This distinctive gene signature was also found in their bone marrow precursors. The NASH myeloid phenotype was principally recapitulated by in vitro exposure ...

Researchers explore the cellular and molecular adaptations associated with human secondary lymphoid tissue in adults during ...

Objective: To investigate the expression and activity of four isotypes of PAD in peripheral blood and synovial fluid cells of patients with RA. Conclusion: PAD2 and PAD4 are the most likely candidate ...

Department of Biomaterials and Biomedical Technology, The Personalized Medicine Research Institute (PRECISION), University Medical Center Groningen, University of Groningen, Ant. Deusinglaan 1, 9713 ...

The manuscript addresses the 3D chromatin architecture in monocytes from patients with alcohol-associated hepatitis and its relationship to enhanced transcription of innate immune genes. While the ...

Gene therapies to treat rheumatoid arthritis have evolved slowly, but one is ready to move into human trials and an ...