1% of mitochondrial proteins are encoded by the mitochondrial genome and synthesized in the mitochondrial matrix. The translocase of the outer membrane (TOM) complex is the main entry gate used by ...

Mitochondria, often seen as cellular powerhouses, play a surprising role in immune regulation. Researchers found that ...

"The intermediate complexes formed during the mitoribosome ... understanding of how the assembly and disassembly of the mitochondrial protein factory takes place and how disruptions occur that ...

mtDNA molecules are compacted into mtDNA-protein complexes termed nucleoids. Mitochondrial nucleoid proteins compact and protect mtDNA and impact mtDNA transcription. Mass spectrometry studies ...

For 1.5 billion years, the mitochondrial ... maintain coadapted gene complexes. Researchers are now coming to appreciate that this has consequences for physiology and even macroevolution. Researchers ...

Cyanobacteria began contributing oxygen to Earth's mostly noxious atmosphere more than 2 billion years ago. The photosystem ...

While significant progress has been made in understanding the protein components of mitochondrial complexes, the role of certain conserved proteins remains enigmatic. Initially identified in ...

We study the molecular mechanism of proteins involved in biological energy conversion and mitochondrial function/dysfunction (respiratory complexes I-V). We apply multi-scale computational approaches ...

The study shows that mitochondria do more than provide energy; they play an active role in modulating the immune response.

This is an important and solid study that examines the role of TFAM, a protein that helps maintain mtDNA, in mtDNA mutator mice. The authors have demonstrated that TFAM's counteractive role in mtDNA ...