Mitochondrial ATP synthase plays a crucial role in energy production within cells, and its regulation is increasingly recognized as a significant factor in cancer metabolism. Recent research has ...

Mitochondria are organelles with two well ... It contains the protein complexes from the electron transport chain, the ATP synthase and the adenine nucleotide translocator (ANT).

Here, using a broad set of in vivo and in vitro measurements using purified enzymes, we find that leucinostatin A, but not lefleuganan, specifically targets the mitochondrial ATP synthase, inhibiting ...

Muscle biopsy at the age of 10 years revealed completely undetectable ATP synthase activity with otherwise normal activities ... complexes were assayed by spectrophotometric methods as described ...

Mitochondria are essential organelles for neuronal function and cell survival. Besides the well-known bioenergetics, additional mitochondrial roles in calcium signaling, lipid biogenesis, regulation ...

A mechanistic understanding of how mitochondrial dysfunction contributes to cell growth and tumorigenesis is emerging beyond Warburg as an area of research that is under-explored in terms of its ...

Mitochondrial dysfunction is involved in numerous diseases and the aging process. The integrated stress response (ISR) serves as a critical adaptation mechanism to a variety of stresses, including ...

Mitochondria contain the mitochondrial electron transport chain (ETC), or a series of protein complexes in which electrons pass through and produce ATP, or energy, for the cell. Mitochondrial ETC ...

Mitochondria organelles came from primordial bacterial endosymbionts and still preserve distinct genes for important functions like making ATP. To speed the emerging therapeutic research into the ...

Convincing evidence, including the image analysis pipeline, indicates that two of these compounds promote mitochondrial elongation and protect against mitochondrial fragmentation caused by chemical ...

A. As of February 2025, Jannik Sinner is the ATP World No. 1. Q. Who won the 2025 Australian Open men's singles title? - + A. A. Jannik Sinner won the 2025 Australian Open men's singles final ...