Microglia, Pediatric Neurology, Autism Spectrum Disorder, Epilepsy, Neuroinflammation, Neurodevelopment Kaur, H. (2025) The Role of Microglia in Pediatric Neurological Disorders. Neuroscience and ...

The main immune cells in the Central Nervous System (CNS) are called microglia and can be considered the brain's resident macrophages. They are, therefore, in charge of triggering inflammation in ...

Elevation of the proinflammatory cytokine Interleukin-1 (IL-1) is an integral part of the local tissue reaction to central nervous system (CNS ... Both astrocytes and microglia undergo cellular ...

Microglia are brain-resident macrophages playing pivotal roles in CNS development and homeostasis. Yet, the cellular and molecular basis governing microglia maintenance ...

(Nasdaq: VIGL), a clinical-stage biotechnology company committed to harnessing the power of microglia for the treatment ... chat at the Stifel 2025 Virtual CNS Forum on Wednesday, March 19 ...

View Full Profile. Learn about our Editorial Policies. This lack of progress has prompted many research groups to look instead at non-neuronal cells in the brain, and in particular, at immune cells ...

Vigil Neuroscience, Inc. (Nasdaq: VIGL), a clinical-stage biotechnology company committed to harnessing the power of microglia for the treatment of neurodegenerative diseases, today announced that ...

A study led by Turkish researcher Pinar Ayata unveiled a critical mechanism involving microglia—specialized immune cells in the brain—that could open new avenues for treating Alzheimer's ...

Tyrosine kinase 2 (TYK2), expressed in astrocytes and microglia, is involved in the activation of pathways triggered by proinflammatory cytokines, such as IL-23, IL-12 and type I interferons (IFNs), ...

CNS diseases represent a growing global health ... In vitro studies have utilized NfL to measure inflammatory toxicity mediated by microglia in response to antisense oligonucleotides, for example.