The histone lysine methyltransferase DOT1L (DOT1-like histone lysine methyltransferase) is responsible for the epigenetic regulation of gene expression through specific methylation of lysine79 residue ...

Tumor immune evasion mechanisms could be reversed by activating intracellular antiviral immune responses. It has been reported that the use of DNA methyltransferase (DNMT) inhibitors combined with ...

Shanghai Allist Pharmaceuticals Co. Ltd. has synthesized protein arginine N-methyltransferase 5 (PRMT5) inhibitors reported to be useful for the treatment of cancer.

These hypoxia-induced pro-fibrotic changes were associated with global DNA hypermethylation, and increased expression of DNA methyltransferase (DNMT) enzymes DNMT1 and DNMT3B. DNMT3B significantly ...

Yerba mate, along with tea and coffee, is one of the world's most popular caffeinated beverages. Widely consumed in South ...

The market for Parkinson’s disease (PD) drugs across the seven major geographies (7MM; USA, France, Germany, Italy, UK and ...

Research analysts at Leerink Partnrs issued their Q1 2025 EPS estimates for shares of Tango Therapeutics in a research report issued to clients and investors on Wednesday, February 5th. Leerink ...

The global Parkinson’s disease (PD) market is expected to grow to $7.9 billion by 2033 from $3.4 billion in 2023, according ...

In the midst of pandemic upheaval, researchers have gained fundamental insights about how the body fends off infections.

The researchers also observed a connection with a deficiency of this “methyltransferase” in a well-known pregnancy complication. In all female mammals, including humans, the growing fetus in ...