Mast cells, residing in tissues and critical for initiating inflammation, are filled with granules containing pro-inflammatory substances. These granules are released upon encountering potential ...

According to Kaplan's team, mast cells contain "granules" loaded with histamines (and other pro-inflammatory agents). When these granules tear open, that can trigger a cascade of inflammatory ...

WHILE examining the histology of tuberculoid and lepromatous skin lesions of leprosy, we noted that there were many cells containing acid-fast granules in the cytoplasm, around the granulomatous ...

In this study, we showed that mucosal mast cells were significantly increased in the terminal ileum, ascending colon and rectum of patients with D-IBS compared with controls. Additionally ...

He explained that mast cells are filled with tiny packages, or granules, each "brimming" with histamine and other compounds that act as signals or activators of inflammatory pathways. When mast ...