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Although Nor Haryati has finished her treatment, doctors were loathe to say she was cancer-free due to the genetic mutation.

Background Hereditary causes of ovarian cancer include Lynch syndrome, which is due to inherited pathogenic variants affecting one of the four mismatch repair genes involved in DNA repair. The aim of ...

The TP53 gene is a gene that is mutated in many cancers. It is the most common gene mutation found in cancer cells. A tumor-suppressor gene, TP53 codes for a protein that inhibits the development and ...

A recent review catalogued and thoroughly discussed available technologies, and we encourage readers to consult this review for information on forward genetic screens using chemical mutagens, TILLING ...

Feb. 6, 2025 — Despite new medication, cystic fibrosis often leads to permanent lung damage. Researchers have discovered that the disease causes changes in the immune system early in life ...

gene analysis; full gene sequence 81202 APC (adenomatous polyposis coli) (e.g., familial adenomatosis polyposis [FAP], attenuated (FAP) gene analysis; known familial variants, 81203 APC (adenomatous ...

The slides were incubated with anti-MLH1 (1:100, Abcam, cat# ab223844), anti-MSH2 (1:8000 ... accounting for differences in mutation context and gene length. We used VCF files generated by Mutect2, ...

familial acute respiratory distress syndrome, ANLN-related, dog (MONDO:1012930) neuromuscular channelopathy, KCNG1-related, cattle (MONDO:1012911) progressive retinal atrophy, FAM161A-related, dog ...