The development of a modular, phage-based expression system optimized for Pseudomonas putida enables stringent, tunable and high yield expressions with minimal cytotoxicity. During urinary tract ...

The α and β diversity of the virome and the virome–bacteriome interaction were analysed. The differential bacteriophages were identified, and their correlations with clinical and immunological ...

Whilst the ultimate outcome of the lytic cycle is production of new phage progeny and death of the host bacterial cell, this is a multistep process involving precise coordination of gene transcription ...

Integration of RT-encoding bacteriophages into host genomes through lysogenic infection is common. This study identified numerous prophages encoding RTs in the complete or nearly complete genomes ...

Mycoplasmas as economically important and pantropic pathogens can cause similar clinical diseases in different hosts by eluding host defense and establishing their niches despite their limited ...

细菌对抗生素的耐药性给社会带来沉重经济和健康负担，探索针对多重耐药菌的新方法迫在眉睫。噬菌体作为细菌的天然捕食者，噬菌体疗法一直被视为治疗耐药菌感染的潜在手段，在尿路感染治疗方面也备受关注。然而，临床实验中噬菌体抗菌治疗 UTI 的效果并不持久。

The virus-to-prokaryote ratio (VPR), which reflects the numerical dominance of viruses over their hosts, has been proposed as a proxy for assessing the relationship between viruses and prokaryotes.

Creative Commons (CC): This is a Creative Commons license. Attribution (BY): Credit must be given to the creator. A key challenge in modern chemistry research is to mimic life-like functions using ...

Creative Commons (CC): This is a Creative Commons license. Attribution (BY): Credit must be given to the creator. Non-Commercial (NC): Only non-commercial uses of the work are permitted. RNA–protein ...