we constructed several rAAV vectors with defined regulatory elements and/or the luciferase reporter gene (Fig. 1). AV.Luc contains only the luciferase transgene and an SV40 poly A signal.

Herein we describe a DNA biosensor that provides a sensitive readout for such low-copy DNA sequences through proximity-mediated reassembly of two independently optimized fragments of NanoLuc ...

vanderbilt.edu Design Tff1-knockout (Tff1-KO) mice, immunohistochemistry, luciferase reporter, qRT-PCR, immunoblot, and phosphatase assays were used to examine the role of TFF1 on β-catenin signalling ...

This reporter virus (rSVA-Nluc) represents a useful tool for rapid and quantitative ... The virus-antibody mixtures were transferred to the 96-well plates containing the cell monolayers. The ...

Furthermore, we identified the effect of SMAD4 on metabolic reprogramming by metabolomics and glucose metabolism gene expression analyses. Dual luciferase reporter assays and chromatin ...

为解决 TP53 移码突变胃癌治疗难题，江南大学附属医院研究人员开展相关研究，发现 GSK690 可抑制 TP53 Frameshift NLS 胃癌细胞生长。该成果为这类患者提供新治疗策略，极具科研价值，推荐大家阅读。

The following is a summary of “Role of NAT10-mediated ac4C acetylation of ENO1 mRNA in glycolysis and apoptosis in non-small ...

为解决大肠杆菌生产流感 NP 时细菌 RNA 带来的安全及一致性问题，华中农业大学的研究人员开展相关研究。他们发现 NP 结合细菌 RNA 增强免疫反应，且开发的 NP 突变体可解决安全问题。该成果为通用流感疫苗研发提供新方向，值得一读。

Dec. 6, 2024 — A newly developed luciferase-based reporter can detect problems in protein translocation and disulfide bond formation in the endoplasmic reticulum (ER). Inspired by natural ...

Maritime Reporter & Engineering News' first edition was published in New York City in 1883 and became our flagship publication in 1939. It is the world’s largest audited circulation magazine ...

New Palestine’s boys basketball team moved up four spots and Greenfield-Central fell two positions in the latest Indiana Basketball Coaches Association poll, released Sunday evening.

The "career criminal" accused of stealing a Super Bowl reporter's credit cards after he was found dead in his Kenner, Louisiana, hotel room earlier this month may be tied to a second man's death ...