1Anhui Provincial Clinical Research Center for Hepatobiliary Diseases, Hefei, China. 2Department of Hepatobiliary Surgery,Centre for Leading Medicine and Advanced Technologies of IHM, The First ...

Upon stimuli, chloride intracellular channel CLIC3 is induced and mitigates intracellular chloride ion lose, thereby controls mitochondrial dysfunction, ROS accumulation, DNA damage, and ...

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you have to have the right combination of ion channels and transporters." More information: Shridhar Sanghvi et al, Functional large-conductance calcium and voltage-gated potassium channels in ...

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In the view of this reviewer, the present work represents a foundational advance in understanding Norrin signaling and the role of Tspan12. It will also serve as an important point of comparison for ...

This is a fundamental study that addresses the key question of how the tetraspanin Tspan12 functions biochemically as a co-receptor for Norrin to initiate β-catenin signaling. The strength of the work ...