"Native leptin produced in the body is short lived," he says. "Therefore, researchers have to give a dose to a mouse every day. Because people are larger, they would have to take it even more often ...

The Knockout Mouse Phenotyping Program (KOMP2) sites at Baylor College of Medicine, Jackson Laboratory, and University of California, Davis, are collaborating with the International Mouse Phenotyping ...

If the chimeras are crossed to the 129 strain from which the embryonic stem cells were generated, a heterozygous knockout mouse on a homogeneous background is created and homozygous knockout mice ...

A knockout mouse is a laboratory mouse in which one or more genes have been turned off or "knocked out." To create a knockout mouse, scientists genetically engineer the animal by disrupting a gene ...