A breakthrough in safely delivering therapeutic DNA to cells could transform treatment for millions suffering from common ...
撰文丨王聪编辑丨王多鱼排版丨水成文脂质纳米颗粒(LNP)在靶向肝,以及脾脏和肺部等主要器官方面已取得成功,但穿越血脑屏障(BBB)仍是一项重大挑战。有效的大脑靶向递送系统对于推进神经疾病基因治疗至关重要,但目前仍受限于低运输效率和核酸稳定性差的问题。
脂质纳米粒(LNP)制备溶液的奥秘:开启 mRNA 疗法优化新征程 在生命科学 ... 成为罕见病治疗领域的新曙光。而脂质纳米粒(Lipid nanoparticles,LNPs)作为 mRNA 疗法的 “黄金搭档”,凭借着独特的优势,成为了核酸递送的先进载体。它能够像 “护盾” 一样包裹 ...
This eBook equips developers with essential knowledge to make informed decisions about lipid selection for LNP formulations.
CAMBRIDGE, Mass., March 25, 2025 /PRNewswire/ -- AccurEdit Therapeutics today announced that its innovative in vivo gene editing product, ART001, has obtained Orphan Drug Designation (ODD) from the ...
Serina Therapeutics (SER) announced that Randall Moreadith, CDO, will present new data at the ACS Spring 2025 Meeting and Expo in San Diego, ...
As we previously discussed, beginning in 2022, a series of patent infringement lawsuits were filed against Moderna and ...
are notable examples of successful implementation of LNP technology, as they used LNPs to deliver antigen-coding mRNA. Today, many other lipid nanoparticle-oligonucleotide formulations have been ...
Findings show potential for new lipid-based delivery formulations as a platform technology for immunizationPhiladelphia, PA, ...