The defect in autophagy by the depletion of axonal mitochondria is one of the main claims in the paper. The authors should work more on describing their results of LC3-II/LC3-I ratio, as there are ...

This study presents a valuable finding on the alterations in the autophagic-lysosomal pathway in a Huntington's disease model. The evidence supporting the claims of the authors is solid. However, the ...

Following the induction of autophagy, an omegasome is formed from the ER by association with ZFYVE1/DFCP1. Next is the formation of a phagophore, which expands to engulf cytoplasmic components, ...

In 2000, it was suggested to me that “Autophagy will be the wave of the future; it will become the new apoptosis.” Few people would have agreed at the time, but this statement turned out to be ...

Oral cancer is a highly malignant disease characterized by recurrence, metastasis, and poor prognosis. Autophagy, a catabolic process induced under stress conditions, has been shown to play a dual ...

While autophagy is relevant to many biological processes and often serves as a gatekeeper of homeostasis, when something goes wrong it can either lead to disease or be activated to fight against it.

复旦大学附属中山医院等多单位的研究人员 Linnan Li、Hao Cheng 等人在《Cell Death Discovery》期刊上发表了题为 “METTL3 regulates autophagy of hypoxia - induced cardiomyocytes by targeting ATG7” 的论文。该研究揭示了 METTL3 ...

1Cellular Degradation Biology Center, College of Medicine, Seoul National University, Seoul, Republic of Korea. 2Department of Biomedical Sciences, College of Medicine, Seoul National University, ...

Department of Chemical Sciences, Tata Institute of Fundamental Research, Mumbai 400005, India ...

LC3 (Little Computer 3) assembly programs that I created for "Introduction to Computing" with Dr. Yale N. Patt Not all of these programs are perfect solutions! LAB-4: NIM is the main project in this ...