The Janus kinase (JAK)/signal transducer and activator of transcription (STAT) signaling pathway plays a key role in immune response and inflammation. More and more studies demonstrated that JAK/STAT ...

They found no direct genetic explanation, but they did find a statistically significant enrichment of genes that are subject to regulatory control of the JAK-STAT signalling pathway among genes whose ...

Why do medications that are supposed to help patients with chronic inflammatory diseases sometimes lead to blood clots?

The study suggests that disturbances in the JAK-STAT signalling pathway, an important communication pathway in the body, may contribute to this side effect. “In the study, we uncover the ...

Of the states that do provide coverage for JAK inhibitors used to treat patients with alopecia, researchers found that prior ...

3 Division of Pediatric Surgery, Department of Pediatrics, Hospital S Joao, Porto, Portugal Background and Aim The process of lung development involves several effectors that exert its action via the ...

ORLANDO -- More than 80% of patients with moderate or severe atopic dermatitis (AD) had at least 75% improvement after 12 ...