On the basis of median [interquartile range] R2* values in MRI (Figure 2 E), iron levels in the SN fell greater in the AT group (from 4.5 [4.2–4.9] at baseline to 3.9 [3.8–4.1] after 6 months ...

An estimated 12,000 children are born with thalassemia major, a severe form of the disease, in India each year, accounting ...

Patients with TDT require frequent blood transfusions and iron chelation therapy throughout their lives and generally don’t survive beyond their late 30s. In trials, Casgevy was shown to improve ...

On a Therapeutic Knife-Edge: Iron Replacement Therapy in Patients With Colorectal Cancer and Iron Deficiency/Anemia ... to explore the feasibility of concurrent luminal iron chelation, to determine ...

Patients on dopaminergic agonists (n, mean daily L-dopa equivalent in mg) 18 (243) 18 (220) 4 (225) 13 (250) Patients on L-dopa and agonists (n) 7 7 2 5 Cognition and behavior: MDS-UPDRS part I ...

The following has been reported so far. Figure 1 outlines the main cardiac injury mechanisms associated with iron overload. The therapy targeting the hepcidin-transferrin axis has demonstrated initial ...

Global Thalassemia Market Global Thalassemia Market Dublin, Jan. 31, 2025 (GLOBE NEWSWIRE) -- The "Thalassemia Market by ...

The Chang Lab at Princeton Chemistry continues in its mission to elucidate the role of metal nutrients in human biology: last year, iron ... to copper chelation. Chelation therapy allows ...

After a decade of relying on blood transfusions for her congenital disorder, 11-year-old Dang Thanh Mai Thu is now recovering ...

As a physician with a long career in alternative medicine and who opposes pharmaceutical marketing, you might think I have a ...

It follows on the heels of a companion July 2024 paper focusing on iron. In this latest work ... consequently vulnerable to copper chelation. Chelation therapy allows scientists to "grab hold ...