吲哚胺 2,3 - 双加氧酶 1（Indoleamine 2,3-dioxygenase 1，IDO1）是一种在免疫调节、肿瘤发生等多种生理病理过程中发挥重要作用的酶。 IDO1 是一种含血红素的单体酶，属于加氧酶家族，能催化色氨酸沿犬尿氨酸途径进行代谢。 人类 IDO1 基因位于 8 号染色体上，编码的 ...

Presentation will include an update on the development and launch preparations of Cylembio™ (imsapepimut and etimupepimut, adjuvanted) NEW YORK, Feb. 20, 2025 (GLOBE NEWSWIRE) -- IO Biotech (Nasdaq: ...

另一方面，cortisol 能 够通过受体激活小胶质细胞和中枢炎症，两者均能 激活吲哚胺 2，3-双加氧酶( indoleamine 2，3-dioxygenase，IDO) 和单胺氧化酶加速单胺类神经递质降 解，从而引起抑郁症状和病理变化。 实验方法 海马干预抑制 CUMS 诱导斑马鱼体内 cortisol 和炎症 ...

为解决慢性偏头痛与共病机制不明及 IDO1 作用不清的问题，南方医科大学研究人员开展 IDO1 相关研究。结果发现 ACC 中的 IDO1 驱动疼痛敏化和焦虑。该研究为慢性偏头痛治疗提供新靶点，极具科研价值，推荐阅读。 在神经科学的研究领域中，偏头痛（Migraine）是一个备受关注的问题。它是一种常见且致残的原发性头痛疾病，全球有大量人口受其困扰。据全球疾病负担研究（2021）显示，偏头痛影响着 ...

3 in games played Lakers star plays in his 1,542nd career game and becomes the 1st player with multiple 40-point games after turning 40. Paul passes Kidd for No. 2 all-time in steals Chris Paul ...

Nintendo Switch 2 is finally confirmed. After literal years of unverified rumors, dubious leaks and copious amounts of online speculation, Nintendo has lifted the lid on its next-generation ...

There are still no details about what Extraction 3 will be about, but the path is set thanks to Extraction 2's ending. The sequel follows Tyler Rake as he achieves an impossible prison break to ...