Key Laboratory for Advanced Materials and Joint International Research Laboratory of Precision Chemistry and Molecular Engineering, Feringa Nobel Prize Scientist Joint Research Center, Frontiers ...

Graduate School of Pharmaceutical Sciences, Tohoku University, Sendai 980-8578, Japan ...

Once in the nucleus the other chaperone proteins dissociate from the AhR leading to canonical or non-canonical signaling. Canonical signaling (left side of the center, dashed line) involves ...

Asthma is one of the major growth areas in therapeutics and many new drugs are currently in development. These drugs include improvements of existing classes of drugs, notably once-daily inhaled ...

The Molecular Mechanics Poisson-Boltzmann Surface Area (MMPBSA) approach has been widely applied as an efficient and reliable free energy simulation method to model molecular recognition, such as for ...

Isatin is still considered to be a promising agent during the planning of new drugs given its low production costs and its chemical structure. The possibility to introduce diverse chemical ...