Some patients with ANCA-associated vasculitis exhibit a dominant anti-MPO response mediated by CD27+IgM+ B-cells, suggesting potential therapeutic targets. Antineutrophil cytoplasmic antibody ...

This investigation elucidated the differences in humoral and H1N1 HA-specific memory B-cells response in participants exhibiting distinct immune response patterns prior to and after vaccination with ...

This important study utilizes humanized mice, in which human immune cells are introduced into immune-deficient mice, to provide convincing evidence that two helper CD4 T-cell subsets, T-follicular ...

Copyright: © 2024 Elsevier Ltd. All rights are reserved, including those for text and data mining, AI training, and similar technologies. Aberrant B-cell function ...

For cell staining, nonspecific antibody binding sites were blocked for 30 min using 25% canine serum and 25% FBS in PBS buffer (without Ca +2 and Mg +2) (Lonza, Walkersville, MD) prior to their ...

What Is B-Cell Lymphoma? B-cell lymphoma is a cancer that forms in your white blood cells called lymphocytes. These cells are made by your lymphatic system, which plays an important role in immunity.

Objectives B-cell depletion time after rituximab (RTX) treatment is prolonged in antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) compared with other autoimmune diseases. We ...

Mar. 11, 2025 — Researchers have identified genetic changes in blood stem cells from frequent blood donors that support the production of new, non-cancerous cells. Understanding the differences ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Metastatic melanoma can be treated with ...