In L2-IL1β mice, p53 mutation increased progenitors expansion and lineage-tracing with a shift from metaplasia to dysplasia. scRNA-seq revealed dysplastic cells arise directly from mutant progenitors ...

BACKGROUND Biopsy specimens obtained from the gastro-oesophageal junction can reveal intestinal metaplasia in patients presenting for routine upper endoscopy. The site of biopsy may play a critical ...

Your esophagus pathology report: Barrett's esophagus and dysplasia. Jencks DS, Adam JD, Borum ML, Koh JM, Stephen S, Doman DB. Overview of current concepts in gastric intestinal metaplasia and ...

Additionally, erosions and cysts may be found in non-neoplastic mucosa. In most prophylactic gastrectomies reported so far, intestinal metaplasia and H pylori infection are absent (families from North ...

Metaplastic columnar epithelium associated with intestinal metaplasia predisposes to adenocarcinoma ... biopsies is used to detect patients with dysplasia and early cancer. Patients with high ...

Chronic inflammation and regeneration processes lead to dysregulation of hepatocyte growth, genomic instability, DNA damage, dysplasia, and malignant transformation, which ultimately lead to HCC. The ...

Human papillomaviruses (HPVs) give rise to a large spectrum of epithelial lesions, mainly benign hyperplasia (e.g ... High-risk HPVs cause cervical dysplasia and carcinoma in situ, which if ...

Objective: To evaluate the role of chromohysteroscopy in improving diagnostic accuracy of endometrial biopsy in cases of AUB. Design: Cross sectional interventional study. Materials and Methods: This ...

Esophageal adenocarcinoma arising from Barrett's metaplasia has regional variations in the west. Gastroenterology 122(2), 588-590 (2002). Haggitt RC. Barrett's esophagus, dysplasia and adenocarcinoma.

This policy statement discusses clinical guidelines for screening of fetuses suspected of manifesting a skeletal dysplasia or for pregnancies at-risk. Historically, in-utero radiographs of a fetus ...

Adenomatous polyps typically do not cause symptoms unless they progress to colon cancer. Even then, there may be no sign of a problem until the malignancy is advanced. This is why colon cancer ...