Our in vitro data indicate that CXCL13 production was increased in human peripheral blood mononuclear cells by anti ... markers and enrichment of pathways associated with a productive antigen ...

Inhibition of nonsense-mediated decay turns immunologically cold tumors hot by increasing the amount of mutant RNA leading to an increase in T-cell-targetable neoantigens on the cell surface.

Antigen presentation is critical to initiate the adaptive immune response to cancer, instigating the immune response by processing tumor antigens and presenting them to T cells of the adaptive immune ...

Feb. 18, 2025 — The immune systems of cancer patients are highly disrupted, with those who have a higher number of immune cells in their blood having a better survival rate, finds a new study ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Studying the human immune system in vivo is ...

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Your immune system includes your body's cells, tissues, and organs, which work together to fight off infections and diseases. But how much do you know about it? When you understand everything that ...

Spyre Therapeutics, Inc. (NASDAQ: SYRE) (the "Company" or "Spyre"), a clinical-stage biotechnology company advancing best-in-class antibody engineering, dose optimization, and rational therapeutic ...

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The human immune system is like an army of specialized soldiers (immune cells) each with a unique role to play in fighting disease. In a new study published in Nature, led by scientists at the ...

It might be cold outside, but athletic kids can still ice skate over break at one of the state's many indoor rinks. Spots ...