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基于转录调控与化学结构挖掘乳腺癌治疗的中药组合新策略
用该模型预测 11 个候选组合的 ZIP 分数,发现 S10S12(Honokiol,HO)和 S2S3(Neochlorogenic acid,NA)组合(简称 HONA)的平均预测分数最高,提示其可能具有潜在的协同效应 。此外,药物 - 药物相互作用(Drug - Drug Interaction,DDI)预测显示 HONA 具有良好的安全性 ...
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